• 熔點： 204-206 °C (dec.)

• 外觀： 黃色針狀晶體

• 溶解性： DMSO：10mg/ml（需超聲）

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 134. [3.8] Chen Yue et al."Impact of ginsenoside Rb1 on gut microbiome and associated changes in pharmacokinetics in rats."Scientific Reports.2024 Sep;14(1):1-12

• 133. [10.6] Xu Yida et al."Berberine and magnolol exert cooperative effects on ulcerative colitis in mice by self-assembling into carrier-free nanostructures."JOURNAL OF NANOBIOTECHNOLOGY.2024 Dec;22(1):1-15

• 132. [2.5] Li Chen et al."Optimization of Extraction Process of Total Alkaloids from Thalictrum delavayi Franch. and Their Therapeutic Potential on Pulmonary Infection Caused by Klebsiella pneumoniae and Escherichia coli."Separations.2024 Jul;11(7):210

• 131. [3] Haiwen Zhang et al."Alkaloid profiling of the new species Corydalis huangshanensis and other 13 medicinal plants in genus Corydalis."PHYTOCHEMICAL ANALYSIS.2024 Jul;:

• 130. [3.4] Changhong Wu et al."Berberine attenuates 5-fluorouracil-induced intestinal mucosal injury by modulating the gut microbiota without compromising its anti-tumor efficacy."Heliyon.2024 Jul;10:

• 129. [4.2] Kaiyue Zhang et al."Mechanisms of Zhixiao Tang on Anti-Inflammatory Multiple Targets and Multiple Components: Metabonomics Combined with Database Mining Technology."Journal of Inflammation Research.

• 128. [4.8] Jie Wang et al."Lycopene alleviates Deoxynivalenol-induced toxicity in Porcine intestinal epithelial cells by mediating mitochondrial function."TOXICOLOGY.2024 Aug;506:153880

• 127. [6.7] Xianli Xu et al."Bu-Shen-Ning-Xin decoction ameliorates premature ovarian insufficiency by suppressing oxidative stress through rno_circRNA_012284/rno_miR-760-3p/HBEGF pathway."PHYTOMEDICINE.2024 Jul;:155920

• 126. [6.7] Guibing Meng et al."Berberine alleviates ulcerative colitis by inhibiting inflammation through targeting IRGM1."PHYTOMEDICINE.2024 Oct;133:155909

• 125. [4.5] Tie Yao et al."Discovery of natural AMPK activator from the fruits of Xanthium sibiricum Patr.: Xanthiumine A, protoberberine alkaloid with unique C28 skeleton."BIOORGANIC CHEMISTRY.2024 Jun;:107527

• 124. [4.9] Xiaoran Zhao et al."Constructing a hydrogel based on self-assembly properties of glycyrrhizic acid: A drug delivery system with digestive tract responsive."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2024 Sep;697:134497

• 123. [IF=4.9] Xueyu Pu et al."Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria."MOLECULAR PHARMACEUTICS".2024;21(5):2238–2249

• 122. [IF=5.4] Sihao Zhang et al."Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118236

• 121. [IF=7.9] Jinqiu Rao et al."Unraveling the enigma: Molecular mechanisms of berberrubine-induced nephrotoxicity reversed by its parent form berberine."PHYTOMEDICINE".2024 Jul;129:155648

• 120. [IF=7.9] Kaifan Hu et al."Effect of Pulsatilla decoction on vulvovaginal candidiasis in mice. Evidences for its mechanisms of action."PHYTOMEDICINE".2024 Mar;:155515

• 119. [IF=5.8] Jiang Sun et al."A self-assembly active nanomodulator based on berberine for photothermal immunotherapy of breast cancer via dual regulation of immune suppression."INTERNATIONAL JOURNAL OF PHARMACEUTICS".2024 Feb;:123898

• 118. [IF=8] Chenqi Chang et al."Combined ROS Responsive Polydopamine-Coated Berberine Nanoparticles Effective Against Ulcerative Colitis in Mouse Model."International Journal of Nanomedicine.10.2147/IJN.S442761

• 117. [IF=3.4] Jiaping Zhang et al."Effect of the Pulsatilla decoction n-butanol extract on vulvovaginal candidiasis caused by Candida glabrata and on its virulence factors."FITOTERAPIA.2024 Mar;173:105825

• 116. [IF=5.4] Wenjuan Ma et al."Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117752

• 115. [IF=7.9] Shan Zhang et al."Enhancing β-Cell Function and Identity in type 2 diabetes: The Protective Role of Coptis deltoidea C. Y. Cheng et Hsiao via Glucose Metabolism Modulation and AMPK Signaling Activation."PHYTOMEDICINE.2024 Jan;:155396

• 114. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284

• 113. [IF=5.4] Botong Li et al."Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 pathways."JOURNAL OF ETHNOPHARMACOLOGY.2024 Mar;322:117578

• 112. [IF=5.9] Jihui Lu et al."Nanoparticles Self-Assembled from Berberine and Chrysin for Generating Antimicrobial Films."ACS Applied Nano Materials.2023;XXXX(XXX):XXX-XXX

• 111. [IF=10.7] Chunfang Zhao et al."An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds."Journal of Advanced Research.2023 Nov;:

• 110. [IF=3.9] LanQing Li et al."Optimized HPLC extraction method of quercetin and berberine based on response surface analysis."RSC Advances.2023 Oct;13(42):29427-29437

• 109. [IF=3.4] Rongrong Li et al."Chemical profiles, Differentiation, and Quality evaluation of Radix et Rhizoma Thalictri Foliolosi based on LC-MS."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.10.1016/j.jpba.2023.115747

• 108. [IF=10] Shan gao et al."Novel Natural Carrier-Free Self-assembled Nanoparticles for Treatment of Ulcerative Colitis by Balancing Immune Microenvironment and Intestinal Barrier."Advanced Healthcare Materials.10.1002/adhm.202301826

• 107. [IF=5.4] Xuemei Wang et al."Combination of Coptis chinensis polysaccharides and berberine ameliorates ulcerative colitis by regulating gut microbiota and activating AhR/IL-22 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Aug;:117050

• 106. [IF=4.6] Fengge YANG et al."Deciphering chemical and metabolite profiling of Chang-Kang-Fang by UPLC-Q-TOF-MS/MS and its potential active components identification."Chinese Journal of Natural Medicines.2023 Jun;21:459

• 105. [IF=5.4] Si-Min Pan et al."Baitouweng decoction repairs the intestinal barrier in DSS-induced colitis mice via regulation of AMPK/mTOR-mediated autophagy."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jul;:116888

• 104. [IF=7.9] Jiangna Yan et al."Blocking LTB4 Signaling-mediated TAMs Recruitment by Rhizoma Coptidis Sensitizes Lung Cancer to Immunotherapy."PHYTOMEDICINE.2023 Jul;:154968

• 103. [IF=3.1] Cuicui Liu et al."Identification and quantitative analysis of the chemical constituents of Gandouling tablets using ultra-high-performance liquid chromatography with quadrupole time-of-flight mass spectrometry."JOURNAL OF SEPARATION SCIENCE.2023 Jun;:2300

• 102. [IF=4.7] Chen Zihan et al."Liquid chromatography-tandem mass spectrometry analysis of a ratio-optimized drug pair of Sophora flavescens Aiton and Coptis chinensis Franch and study on the mechanism of anti-colorectal cancer effect of two alkaloids thereof."Frontier

• 101. [IF=6.5] Wei Liu et al."Genome-wide analysis of bHLH gene family in Coptis chinensis provides insights into the regulatory role in benzylisoquinoline alkaloid biosynthesis."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2023 Aug;201:107846

• 100. [IF=3.571] Ning Zhou et al."Exploring the efficacy mechanism and material basis of three processed Coptidis Rhizoma via metabolomics strategy."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Aug;232:115450

• 99. [IF=3.776] Lele Zhang et al."Integration of UHPLC/Q-OrbitrapMS-based metabolomics and activities evaluation to rapidly explore the anti-inflammatory components from lasianthus.."Heliyon.2023 May;9(6):e16117-e16117

• 98. [IF=5.988] Yuanmei Bai et al."Mechanisms of Yajieshaba in the treatment of liver fibrosis through the Keap1-Nrf2 signaling pathway."Frontiers in Pharmacology.2023; 14: 1124015

• 97. [IF=6.656] Ning Zhou et al."Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking."PHYTOMEDICINE.2023 Jun;114:154804

• 96. [IF=10.75] Chen Haitao et al."Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine."International Journal of Biological Sciences.2023 Apr;19(7):2097-2113

• 95. [3.614] Vinay Naithani et al."Preparation of open tubular capillary column covalently coated with polystyrene sulfonate with 4,4′-Azobis(4-cyanopentanoyl chloride) as polymerization initiator for electrochromatographic separation of alkaloids, sulfonamides, and p

• 94. [5.195] Ruyi Chen et al."Component identification of modified sanmiao pills by UPLC-Xevo G2-XS QTOF and its anti-gouty arthritis mechanism based on network pharmacology and experimental verification."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jul;311:116394

• 93. [6.208] Chang Wang et al."Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(7):6364

• 92. [3.614] Yumin Cao et al."Comparative pharmacokinetic studies of Ephedra herba in common cold and nephrotic syndrome rat models."JOURNAL OF SEPARATION SCIENCE.2023 Feb;:2200895

• 91. [5.195] Xiaoxuan Liu et al."Interaction between Changan Granule and its main components in the plasma and CYP450 enzymes."JOURNAL OF ETHNOPHARMACOLOGY.2023 May;308:116303

• 90. [9.429] Zhu Ke et al."Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation."JOURNAL OF NANOBIOTECHNOLOGY.2023 Dec;21(1):1-17

• 89. [0] Xiaoming Yin et al."Assessment of alkaloids from the stems of 14 Berberis species in China."Separation Science Plus.2022 Dec;:202200114

• 88. [5.195] Kaifan Hu et al."Effects of n-butanol extract of Pulsatilla decoction on the NLRP3 inflammasome in macrophages infected with Candida albicans."JOURNAL OF ETHNOPHARMACOLOGY.2022 Dec;:116041

• 87. [4.927] Yaqi Xu et al."The Taste-Masking Mechanism of Chitosan at the Molecular Level on Bitter Drugs of Alkaloids and Flavonoid Glycosides from Traditional Chinese Medicine."MOLECULES.2022 Jan;27(21):7455

• 86. [5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919

• 85. [IF=4.81] Li Shi-ying et al."Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancer."JOURNAL OF PHARMACY AND PHARMACOLOGY.2022 Sep;:

• 84. [IF=6.388] Ping-Yuan Ge et al."Berberine ameliorates depression-like behavior in CUMS mice by activating TPH1 and inhibiting IDO1-associated with tryptophan metabolism."PHYTOTHERAPY RESEARCH.2022 Sep;:

• 83. [IF=2.838] Wang Shuo et al."Toxicity and toxicokinetics of the ethanol extract of Zuojin formula."BMC Complementary Medicine and Therapies.2022 Dec;22(1):1-14

• 82. [IF=5.195] Xinyu Xiong et al."HuanglianGanjiang Tang alleviates DSS-induced colitis in mice by inhibiting necroptosis through vitamin D receptor."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;298:115655

• 81. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS

• 80. [IF=5.988] Yang Sa et al."Berberrubine, a Main Metabolite of Berberine, Alleviates Non-Alcoholic Fatty Liver Disease via Modulating Glucose and Lipid Metabolism and Restoring Gut Microbiota."Frontiers in Pharmacology.2022 Jul;0:2101

• 79. [IF=6.107] Shi-Hai Yan et al."Chemoproteomics reveals berberine directly binds to PKM2 to inhibit the progression of colorectal cancer."iScience.2022 Jul;:104773

• 78. [IF=6.656] Ye Yang et al."Coptis chinensis polysaccharides dynamically influence the paracellular absorption pathway in the small intestine by modulating the intestinal mucosal immunity microenvironment."PHYTOMEDICINE.2022 Sep;104:154322

• 77. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177

• 76. [IF=2.01] Wang Xiaoqi et al."Inhibition of Berberine on Methicillin-Resistant Staphylococcus aureus Biofilm Formation."Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy. 2022 Apr;:1-5

• 75. [IF=4.617] Li Ziwei et al."Baicalin-berberine complex nanocrystals orally promote the co-absorption of two components."Drug Delivery and Translational Research. 2022 Apr;:1-12

• 74. [IF=1.978] Yue Shi-jun et al."Anti-obesity and Gut Microbiota Modulation Effect of Astragalus Polysaccharides Combined with Berberine on High-Fat Diet-Fed Obese Mice."Chin J Integr Med. 2021 Dec;:1-9

• 73. [IF=5.165] Juanning Ren et al."Qualitative and quantitative analysis of multi-components in Xing-Su-Ning Capsules for quality improvement."Arab J Chem. 2022 Jun;15:103825

• 72. [IF=10.479] Shiyun Chen et al.Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis.J Adv Res. 2021 Nov;:

• 71. [IF=1.345] Ya-Li Zhang et al."Coptisine suppresses proliferation and inhibits metastasis in human pancreatic cancer PANC-1 cells."J Asian Nat Prod Res. 2020;22(5):452-463

• 70. [IF=2.01] Lin Li et al."Pharmacokinetic Studies of Multiple Active Components in Rat Plasma Using LC-MS/MS after Oral Administration of Shaoyao-Gancao-Fuzi Decoction."Rev Bras Farmacogn. 2020 Dec;30(6):810-817

• 69. [IF=2.351] Juanjuan Liu et al."Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris."Biofouling. 2020;36(3):319-331

• 68. [IF=2.461] Huang Xue-Jiao et al."The Antibacterial Properties of 4, 8, 4′, 8′-Tetramethoxy (1,1′-biphenanthrene) -2,7,2′,7′-Tetrol from Fibrous Roots of Bletilla striata."Indian J Microbiol. 2021 Jun;61(2):195-202

• 67. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535

• 66. [IF=3.004] Kai Zhang et al."Untargeted metabolomics reveals the synergistic mechanisms of Yuanhu Zhitong oral liquid in the treatment of primary dysmenorrhea."J Chromatogr B. 2021 Feb;1165:122523

• 65. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585

• 64. [IF=3.69] Qianni Duan et al."Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2."J Ethnopharmacol. 2020 Mar;249:112405

• 63. [IF=3.845] Wang Kaifu et al."Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinergic Anti-Inflammatory Pathway in Diabetic Rats."Front Pharmacol. 2019 Sep;10:1003

• 62. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820

• 61. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51

• 60. [IF=4.432] Zulong Xie et al."Remodelling of gut microbiota by Berberine attenuates trimethylamine N-oxide-induced platelet hyperreaction and thrombus formation."Eur J Pharmacol. 2021 Nov;911:174526

• 59. [IF=4.545] Wei Li et al."Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination."Biomed Pharmacother. 2020 Jan;121:109563

• 58. [IF=4.545] Haitao Chen et al."Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota."Biomed Pharmacother. 2020 Apr;124:109829

• 57. [IF=4.759] Rong Wang et al."Integration of micro-fractionation, high-performance liquid chromatography-ultraviolet detector-charged aerosol detector-mass spectrometry analysis and cellular dynamic mass redistribution assay to accelerate alkaloid drug discovery."J Ch

• 56. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625

• 55. [IF=5.085] Haitao Chen et al."A Holistic View of Berberine Inhibiting Intestinal Carcinogenesis in Conventional Mice Based on Microbiome-Metabolomics Analysis."Front Immunol. 2020; 11: 588079

• 54. [IF=5.396] Yuan Liang et al."Glucocorticoid receptor-mediated alleviation of inflammation by berberine: in vitro, in silico and in vivo investigations."Food Funct. 2021 Oct;:

• 53. [IF=7.691] Xizhan Xu et al."Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine."Genom Proteom Bioinf. 2020 Dec;18:721

• 52. [IF=9.811] Manjie Gao et al."High-Crystallinity Covalent Organic Framework Synthesized in Deep Eutectic Solvent: Potentially Effective Adsorbents Alternative to Macroporous Resin for Flavonoids."Chem Mater. 2021;33(20):8036–8051

• 51. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139

• 50. [IF=2.882] Kun Wang et al."Identification of berberrubine metabolites in rats by using ultra-high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry."Fitoterapia. 2018 Jan;124:23

• 49. [IF=2.896] Shun Liu et al."Effects of ultrahigh pressure extraction conditions on yields of berberine and palmatine from cortex Phellodendri amurensis."Anal Methods-Uk. 2013 Aug;5(17):4506-4512

• 48. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239

• 47. [IF=4.411] Jinjun Shan et al."Liquid Chromatography Coupled with Linear Ion Trap Hybrid OrbitrapMass Spectrometry for Determination of Alkaloids in Sinomeniumacutum."Molecules. 2018 Jul;23(7):1634

• 46. [IF=4.759] Lvhuan Wang et al."Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined with liquid chromatography-mass spectrometry."J Chromatogr A. 2018 Aug;1563:135

• 45. [IF=6.057] Zhihong Li et al."New MS network analysis pattern for the rapid identification of constituents from traditional Chinese medicine prescription Lishukang capsules in vitro and in vivo based on UHPLC/Q-TOF-MS."Talanta. 2018 Nov;189:606

• 44. Raji, P. , et al. "Antibacterial Activity of Alkaloids, Flavonoids, Saponins and Tannins Mediated Green Synthesised Silver Nanoparticles Against Pseudomonas aeruginosa and Bacillus subtilis." Journal of Cluster Science 30.5(2019).DOI： 10.1007/s10876-019-01

• 43. Wang, Kaifu, et al. "Berberine ameliorates spatial learning memory impairment and modulates cholinergic anti-inflammatory pathway in diabetic rats." Frontiers in pharmacology 10 (2019): 1003.https://doi.org/10.3389/fphar.2019.01003

• 42. Li, Wei, et al. "Berberine increases glucose uptake and intracellular ROS levels by promoting Sirtuin 3 ubiquitination." Biomedicine & Pharmacotherapy 121 (2020): 109563.https://doi.org/10.1016/j.biopha.2019.109563

• 41. Chen, Haitao, et al. "Berberine regulates fecal metabolites to ameliorate 5-fluorouracil induced intestinal mucositis through modulating gut microbiota." Biomedicine & Pharmacotherapy 124 (2020): 109829.https://doi.org/10.1016/j.biopha.2020.109829

• 40. Zhou, Xiao-Yuan, et al. "In vitro characterization and inhibition of the interaction between ciprofloxacin and berberine against multidrug-resistant Klebsiella pneumonia e."?The Journal of antibiotics?69.10 (2016): 741-746.

• 39. Lvhuan Wang, Yumei Zhao, Yanyan Zhang, Tingting Zhang, Jeroen Kool, Govert W. Somsen, Qiqin Wang, Zhengjin Jiang, Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined wi

• 38. Zhang, Qijiayu, et al. "Combination of Berberine and Matrine Affects Apoptosis and Cellcycle in Human Cervical Cancer Cells." Acta Poloniae Pharmaceutica-Drug Research 76.6 (2019): 1089-1097.http://dx.doi.org/10.32383/appdr/112478

• 37. Duan, Qianni, et al. "Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2." Journal of ethnopharmacology 249 (2020): 112405.https://doi.org/10.1016/j.jep.2019.112405

• 36. 康念欣,袁炎炎,張瀟,路穎慧,李晴霞,李飛,譚鵬.酒黃連HPLC特征圖譜的建立及聚類分析和主成分分析[J].世界科學(xué)技術(shù)-中醫(yī)藥現(xiàn)代化,2020,22(08):2790-2798.

• 35. 紀(jì)萬里,周澤華,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏瀉心湯化學(xué)成分[J].藥物分析雜志,2020,40(10):1736-1750.

• 34. 張青青,陳青青,任蓉蓉,楊曄,尹登科.基于尤斯室技術(shù)研究黃連水煎液中微粒體系對小檗堿腸黏膜透過特性的影響及相關(guān)機(jī)制[J].中國藥學(xué)雜志,2021,56(03):189-194.

• 33. 范春芳,郭一沙,王嘉歡,李平,張海龍.黃連素對糖尿病大鼠胰島素抵抗的治療作用[J].中國應(yīng)用生理學(xué)雜志,2020,36(06):561-564.

• 32. 馬月娥,劉春秋.小檗堿對糖尿病認(rèn)知功能障礙模型小鼠AGEs/RAGE/NF-κB信號通路的影響[J].西部中醫(yī)藥,2021,34(02):26-31.

• 31. 李燦, 唐利軍, 茹琴,等. 戒毒一號的高效液相色譜指紋圖譜研究[J]. 江漢大學(xué)學(xué)報(自然科學(xué)版), 2018, 46(05):471-476.

• 30. 李聽弦 李蒙 張志 等. 一測多評法測定不同味連飲片中6個生物堿類成分的含量[J]. 藥物分析雜志 2018 038(007):1132-1138.

• 29. 張瀟, 張亞麗, 苗祥貞,等. 黃連不同炮制品及組分的抗腫瘤活性與6種生物堿含量相關(guān)性研究[J]. 中華中醫(yī)藥雜志, 2019, v.34(06):350-353.

• 28. 李亞杰, 龍瀾, 楊永康,等. 恩施道地藥材黃連的質(zhì)量標(biāo)準(zhǔn)研究[J]. 湖北民族學(xué)院學(xué)報:自然科學(xué)版, 2012, 000(004):443-445.

• 27. 吳甜鶯, 戴歌心, 鄭雷,等. 寧泌泰膠囊及其有效單體對炎癥相關(guān)STAT3信號通路的抑制作用[J]. 上海中醫(yī)藥大學(xué)學(xué)報, 2018, 32(05):69-72.

• 26. 張久旭, 范晶, 李小陽,等. 基于內(nèi)在品質(zhì)的黃連藥材現(xiàn)代產(chǎn)地加工方法研究[J]. 遼寧中醫(yī)藥大學(xué)學(xué)報, 2019, v.21;No.185(09):74-77.

• 25. 薛夢瑩 李璐 張華峰 劉紫祺.3種小檗科植物類黃酮、生物堿含量與抑菌活性的季節(jié)變化規(guī)律[J].草業(yè)科學(xué) 2018 35(11):2614-2621.

• 24. 趙露, 江健梅, 孟琦,等. 白屈菜生育期內(nèi)生物堿含量的變化規(guī)律[J]. 吉林農(nóng)業(yè)大學(xué)學(xué)報, 2017(5):590-595.

• 23. 李璐, 安葉娟, 喬春雷,等. 淫羊藿生物堿的超聲波-微波協(xié)同提取及其對HeLa細(xì)胞的抑制作用[J]. 植物學(xué)報, 2018, 053(003):341-352.

• 22. 劉珍珍 白橋 徐皓. 不同初加工方法對延胡索5種生物堿含量的影響[J]. 現(xiàn)代農(nóng)業(yè)科技 2019 000(022):173-176.

• 21. 張園園, 嚴(yán)君君, 張培,等. 黃連素調(diào)節(jié)腸道菌群減輕非酒精性脂肪性肝病肝臟炎癥的實驗研究[J]. 胃腸病學(xué), 2018, 023(004):209-215.

• 20. 呂媛媛, 陳子龍, 馬慧璇. 黃連素對鏈脲佐菌素糖尿病大鼠GH/IGF-Ⅰ軸的影響[J]. 齊齊哈爾醫(yī)學(xué)院學(xué)報, 2019, 40(13):1585-1588.

• 19. 韓菊梅, 張偉錚. 黃連素與環(huán)丙沙星協(xié)同抑制銅綠假單胞菌生物膜的作用研究[J]. 廣州醫(yī)學(xué)院學(xué)報, 2018, 046(006):65-66,70.

• 18. 焦放, 侯子言, 尹登科,等. 黃連水煎液中固體微粒對小檗堿在體腸吸收特性的影響研究[J]. 中草藥, 2016, 47(008):1357-1360.

• 17. 孫磊, 李照, 吳懷秀,等. 重組人乙酰膽堿酯酶體外表達(dá)制備及其相關(guān)小分子活性篩選[J]. 藥物分析雜志, 2019(3):386-392.

• 16. 陳智,劉玉珍,齊博,劉尚國,趙寶生.聯(lián)合應(yīng)用小檗堿和二甲雙胍對miR-212介導(dǎo)的食管癌細(xì)胞遷移的影響[J].中國老年學(xué)雜志,2019,39(11):2735-2739.

• 15. 朱超霞 倉楨 加孜熱亞·再依拿提 李琴 夏芳珍 陸穎理. 鹽酸小檗堿對高脂飲食誘導(dǎo)的非酒精性脂肪性肝病大鼠腸道菌群的影響[J]. 上海交通大學(xué)學(xué)報(醫(yī)學(xué)版), 2015(35):483-488.

• 14. 戴晶晶, 朱建勇, 張春燕,等. 正交試驗優(yōu)選冬柏通淋顆粒提取工藝[J]. 亞太傳統(tǒng)醫(yī)藥, 2017, 013(008):26-29.

• 13. 徐偉軍. 小渠堿對膽道感染糞腸球菌的生物被膜形成及毒力基因表達(dá)影響[J]. 中國衛(wèi)生檢驗雜志, 2018, 28(21):2622-2625.

• 12. 沈雁, 王章流, 鄭華君,等. 小檗堿調(diào)控內(nèi)質(zhì)網(wǎng)應(yīng)激水平影響UC結(jié)腸炎癥反應(yīng)的實驗研究[C]// 第三十屆全國中西醫(yī)結(jié)合消化系統(tǒng)疾病學(xué)術(shù)會議. 0.

• 11. 陳靜, 李威, 樊銳鋒,等. 小檗堿抑制體外培養(yǎng)的人翼狀胬肉成纖維細(xì)胞遷移能力的機(jī)制研究[J]. 中醫(yī)藥導(dǎo)報, 2019(22).

• 10. 李威, 張旭, 趙芳園,等. 小檗堿對葡萄糖誘導(dǎo)的HEPG2細(xì)胞功能的調(diào)節(jié)機(jī)制[J]. 醫(yī)學(xué)研究雜志, 2020, 049(002):99-105.

• 9. 張敬升, 黃偉, 謝鳴. 小檗堿對體外HepG2細(xì)胞IR模型抗IR的效應(yīng)及機(jī)制[J]. 中國實驗方劑學(xué)雜志, 2018(21).

• 8. 李玲,盧芳國,陳伶利,向琴,高強(qiáng),魏科,胡玨,寧毅.小檗堿體外抗耐甲氧西林金黃色葡萄球菌活性的研究[J].湖南中醫(yī)藥大學(xué)學(xué)報,2018,38(03):254-256.

• 7. 侯子言, 焦放, 楊曄,等. 殼聚糖粒子對小檗堿在體腸吸收的影響[J]. 中國實驗方劑學(xué)雜志, 2016(10):11-14.

• 6. 吳晶晶, 袁秀妍, 楊曄. 基于小腸M細(xì)胞模型研究黃連多糖對小檗堿經(jīng)小腸吸收的影響及相關(guān)機(jī)制[J]. 中南藥學(xué), 2020, v.18;No.171(04):7-12.

• 5. 李桐, 王輝, 張昊,等. 基于分子熱力學(xué)特征探討黃連解毒湯水煎自沉淀形成機(jī)制[J]. 中草藥, 2017(17).

• 4. 許巖 賀永桓 鄭舒文 等. 以黃連素/羥丙基-β-環(huán)糊精為熒光探針檢測金剛烷胺[J]. 核農(nóng)學(xué)報 2019 v.33(07):98-103.

• 3. 丁世豪 李真真 王石雄 等. 不同劑量小檗堿對大鼠梗死后心肌組織的保護(hù)作用[J]. 重慶醫(yī)科大學(xué)學(xué)報 2011 36(010):1205-1208.

• 2. 超 張振秋 侯學(xué)智 等. HPLC測定大黃、黃連藥對提取物中10種成分的含量[J]. 中國實驗方劑學(xué)雜志 2013 019(007):98-102.

• 1. 王慧竹 王肅樊 鄧博文 等. HPLC法同時測定清肺抑火丸中9種成分的含量[J]. 中藥材 2018 041(003):652-656.

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *