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• 介紹：

   Bafilomycin A1 (BafA1) 是特異性，可逆的 V-ATPase 抑制劑，IC₅₀ 值為 4-400 nmol/mg。Bafilomycin A1，大環(huán)內(nèi)酯類抗生素， 是一種自噬 (autophagy) 晚期階段抑制劑。Bafilomycin A1 阻斷自噬體與溶酶體的融合，并抑制培養(yǎng)細(xì)胞溶酶體中的酸化和蛋白質(zhì)降解。Bafilomycin A1 也誘導(dǎo)調(diào)亡 (apoptosis)。

• 溶解性： DMSO  :  100  mg/mL  (160.56  mM;  Need  ultrasonic)
  
  H2O  :  <  0.1  mg/mL  (ultrasonic;warming;heat  to  60°C)  (insoluble)

• 敏感性： 對熱和光敏感

• 儲(chǔ)存條件： -20℃

• 用途： A macrolide antibiotic and potent and selective inhibitor of vacuolar-type (v-type) H+ ATPase

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• 5. [IF=5.9] Zekun Zhou et al."Molecular Mechanism of Calycosin Inhibited Vascular Calcification."Nutrients.2024 Jan;16(1):99

• 4. [5.913] Huang Xiaoping et al."Reactive oxygen species enhance rAAV transduction by promoting its escape from late endosomes."Virology Journal.2023 Dec;20(1):1-17

• 3. [IF=3.056] Y. Liu et al."A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome."Neuroscience. 2014 Dec;281:88

• 2. Y. Liu, W. Duan, Y. Guo, Z. Li, H. Han, S. Zhang, P. Yuan, C. Li, A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome, Neuroscience, Volume 281, 2014, Pages 88-98, ISSN 0306-4522, htt

• 1. Zhou, Junpei, et al. "Characterization of a NaCl-tolerant β-N-acetylglucosaminidase from Sphingobacterium sp. HWLB1." Extremophiles 20.4 (2016): 547-557.https://doi.org/10.1007/s00792-016-0848-4

輸入產(chǎn)品批號：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *