S80423 |
Cyclo(-Arg-Gly-Asp-D-Phe-Lys) |
源葉(MedMol) | 98% |
- 提示:詳情請下載說明書。
- 產(chǎn)品描述: Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface
- 靶點: αvβ3:0.94 nM (IC50);Integrin
- 參考文獻:
1. Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95. 2. Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14.
- 溶解性: DMSO : 125 mg/mL (207.07 mM; Need ultrasonic) H2O : 50 mg/mL (82.83 mM; Need ultrasonic)
- 保存條件: 2-8℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 1.657 ml 8.283 ml 16.565 ml 5 mM 0.331 ml 1.657 ml 3.313 ml 10 mM 0.166 ml 0.828 ml 1.657 ml 50 mM 0.033 ml 0.166 ml 0.331 ml
- 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。
輸入產(chǎn)品批號:
本計算器可幫助您計算出特定溶液中溶質的質量、溶液濃度和體積之間的關系,公式為:
質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)