S85190 |
CMPDA |
源葉(MedMol) | 98% |
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- 產(chǎn)品描述: CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor).
- 靶點(diǎn): GluR
- 體外研究:
CMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation.
- 參考文獻(xiàn):
1. Timm DE, et al. Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation. Mol Pharmacol. 2011 Aug;80(2):267-80.
- 溶解性: Soluble in DMSO
- 保存條件: -20℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 2.656 ml 13.279 ml 26.558 ml 5 mM 0.531 ml 2.656 ml 5.312 ml 10 mM 0.266 ml 1.328 ml 2.656 ml 50 mM 0.053 ml 0.266 ml 0.531 ml
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輸入產(chǎn)品批號(hào):
本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系,公式為:
質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)